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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A

phenylacetyl-CoA + L-Gln → phenylacetyl glutamine + CoA-SH

Reactome: R-HSA-177160
Compartment: mitochondrial matrix
Rhea: RHEA:21845

Inputs

phenylacetyl-CoACHEBI:57390, C29H38N7O17P3S, mitochondrial matrix
L-GlnCHEBI:58359, C5H10N2O3, mitochondrial matrix

Outputs

phenylacetyl glutamineCHEBI:58310, C13H15N2O4, mitochondrial matrix
CoA-SHCHEBI:57287, C21H32N7O16P3S, mitochondrial matrix

Catalysed by

L-glutamine N-acyltransferase activity of glutamine-N-acyltransferase [mitochondrial matrix]EC 2.3.1.68

Literature

Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man J Biol Chem, 1976