Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

SULTs transfer (SO4)2- group to PREG

PREG + PAPS → PREGS + PAP

Reactome: R-HSA-176517
Compartment: cytosol
Rhea: RHEA:52357

Inputs

PREGCHEBI:16581, C21H32O2, cytosol
PAPSCHEBI:58339, C10H11N5O13P2S, cytosol

Outputs

PREGSCHEBI:35420, C21H32O5S, cytosol
PAPCHEBI:58343, C10H11N5O10P2, cytosol

Catalysed by

steroid sulfotransferase activity of SULTs active on pregnenolone [cytosol]EC 2.8.2.15

SULTs transfer (SO4)2- group to PREG

Inputs

Outputs

Catalysed by

Literature