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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen

UDP-GlcA + UDP-GlcNAc → UDP-GlcA + UDP-GlcNAc

Reactome: R-HSA-174368
Compartment: endoplasmic reticulum membrane
Rhea: RHEA:73703

Inputs

UDP-GlcACHEBI:58052, C15H19N2O18P2, cytosol
UDP-GlcNAcCHEBI:57705, C17H25N3O17P2, cytosol

Outputs

UDP-GlcACHEBI:58052, C15H19N2O18P2, endoplasmic reticulum lumen
UDP-GlcNAcCHEBI:57705, C17H25N3O17P2, endoplasmic reticulum lumen

Catalysed by

UDP-glucuronate transmembrane transporter activity of SLC35D1 hexamer [endoplasmic reticulum membrane]

Literature

Molecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity FEBS Lett, 2001