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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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UDP-glucose is oxidised to UDP-glucuronate

UDP-Glc + 2 NAD+ + H2O → UDP-GlcA + 2 NADH + 3 H+

Reactome
R-HSA-173597
Compartment
cytosol
Rhea
RHEA:23597

Inputs

Outputs

Catalysed by

  • UDP-glucose 6-dehydrogenase activity of 6xUGDH [cytosol]EC 1.1.1.22

Literature

  1. Characterization of human UDP-glucose dehydrogenase. CYS-276 is required for the second of two successive oxidations J Biol Chem, 2004