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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

Data

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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]

Cyt-Rib, Ura-Rib + ATP → CMP, UMP + ADP + H+

Reactome: R-HSA-109903
Compartment: cytosol
Rhea: RHEA:24675, RHEA:16826

Inputs

Cyt-Rib, Ura-RibR-ALL-500759, cytosol
ATPCHEBI:30616, C10H12N5O13P3, cytosol

Outputs

CMP, UMPR-ALL-500761, cytosol
ADPCHEBI:456216, C10H12N5O10P2, cytosol
H+CHEBI:15378, H, cytosol

Catalysed by

nucleoside kinase activity of UCK2 tetramer [cytosol]

Literature