Source assertion

PDBe/SIFTS maps PDB 8Q19 to UniProt Q16790 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:8Q19:UNIPROT:Q16790
Subject dossier: ca9
Source chain: uniprot + pdbe
Upstream record: 8Q19
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: In this release

Experimental structure

The Crystal Structure of Human Carbonic Anhydrase IX in Complex with Sulfonamide

PDB ID: 8Q19
Experimental method: X-ray diffraction
Resolution: %!f(*float64=0x24b069b18290) Å
SIFTS identifier: CAH9_HUMAN
Deposited: 20230731
Released / revised: 20231108 / 20241106

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	99.0%	60.4%	137–391
1	`B`	`B`	99.0%	60.4%	137–391
1	`C`	`C`	99.0%	60.4%	137–391
1	`D`	`D`	99.0%	60.4%	137–391

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A, B, C, D / A, B, C, D	Carbonic anhydrase 9polypeptide(L)	257 residues	C41S, N213Q	Genetically manipulated

Reading this structure

This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.

Snapshot provenance

Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:33Z	`raw/uniprot/entries/Q16790.json`	`77abc0523fc4c2b797ea15d860a4bb98365bcf0caec1ee88ba765973570f1f22`	Open exact source
2026-07-14T09:22:01Z	`raw/pdbe/mappings/8q19.json`	`5148eda6df783f4dd42bbce55a5b53a0d38738b519bcfaabe6518b2d45004499`	Open exact source
2026-07-14T09:22:17Z	`raw/pdbe/summary/chunk-04.json`	`9993579d3f578cc0a0be921bfc6aa7a181fb8a074c2cd246c08a1da9b7d92dfc`	Open exact source
2026-07-14T09:22:18Z	`raw/pdbe/experiment/chunk-04.json`	`9fbf526866182ab693088d3c63735d5e62302d743c66532fd0163f0cb378a25b`	Open exact source
2026-07-14T09:22:19Z	`raw/pdbe/molecules/chunk-04.json`	`3e3b75bb7fa19acefd58e3b24f2d7e54feb541eeb253bea88d1e20ba0ccd936c`	Open exact source