About this dossier

UniProt-reviewed human alpha-carbonic-anhydrase scope record. Ectodomain constructs, full-length protein and cell-based contexts remain separate. This release links 11 source records to this accession, a selection rather than every record the upstream databases hold.

Normalized identity

Gene: CA9
UniProt accession: Q16790
Catalytic status: Catalytic
Review state: UniProt-reviewed
Taxon: 9606
Entry version: 218, updated 2026-06-10
Sequence identity: v2, CRC64 BA67195483F0F5CE
Sequence length: 459 residues
Selected structures: 8
Selected activities: 2
Reaction assignments: 1
ChEMBL targets: CHEMBL3594

Where the identity data came from

Each row is a UniProt snapshot used to build this release: when it was retrieved, its SHA-256 digest and the exact request. The snapshot files stay with the build and are not served here.

Retrieved	Build-input snapshot	SHA-256	Upstream request
2026-07-14T09:21:33Z	`raw/uniprot/entries/Q16790.json`	`77abc0523fc4c2b797ea15d860a4bb98365bcf0caec1ee88ba765973570f1f22`	Open exact source

Source-reported location comments

Nucleus
Nucleus, nucleolus
Cell membrane · Single-pass type I membrane protein
Cell projection, microvillus membrane · Single-pass type I membrane protein

UniProt function text

Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions)

Evidence records