Source assertion

PDBe/SIFTS maps PDB 6BC9 to UniProt P00918 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:6BC9:UNIPROT:P00918
Subject dossier: ca2
Source chain: uniprot + pdbe
Upstream record: 6BC9
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: In this release

Experimental structure

Joint X-ray/neutron structure of human carbonic anhydrase II in complex with dorzolamide

PDB ID: 6BC9
Experimental method: Neutron Diffraction, X-ray diffraction
Resolution: %!f(*float64=0x2eca05fefc68) Å
SIFTS identifier: CAH2_HUMAN
Deposited: 20171020
Released / revised: 20180228 / 20251112

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	100.0%	100.0%	1–260

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A / A	Carbonic anhydrase 2polypeptide(L)	260 residues	not reported by the source	Genetically manipulated

Reading this structure

This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.

Snapshot provenance

Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:31Z	`raw/uniprot/entries/P00918.json`	`ed44906dd1b976f4c8b0399e9e3a7a4af09b673c035a201e218a4880821c1179`	Open exact source
2026-07-14T09:21:45Z	`raw/pdbe/mappings/6bc9.json`	`8675fbb7dbeba014a81113bd6b8e0c1f91e2414509e097acdf8d48aa71956da9`	Open exact source
2026-07-14T09:22:17Z	`raw/pdbe/summary/chunk-04.json`	`9993579d3f578cc0a0be921bfc6aa7a181fb8a074c2cd246c08a1da9b7d92dfc`	Open exact source
2026-07-14T09:22:18Z	`raw/pdbe/experiment/chunk-04.json`	`9fbf526866182ab693088d3c63735d5e62302d743c66532fd0163f0cb378a25b`	Open exact source
2026-07-14T09:22:19Z	`raw/pdbe/molecules/chunk-04.json`	`3e3b75bb7fa19acefd58e3b24f2d7e54feb541eeb253bea88d1e20ba0ccd936c`	Open exact source