Source assertion

PDBe/SIFTS maps PDB 5C8I to UniProt P00918 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:5C8I:UNIPROT:P00918
Subject dossier: ca2
Source chain: uniprot + pdbe
Upstream record: 5C8I
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: In this release

Experimental structure

Joint X-ray/neutron structure of Human Carbonic Anhydrase II in complex with Methazolamide

PDB ID: 5C8I
Experimental method: Neutron Diffraction, X-ray diffraction
Resolution: %!f(*float64=0x24b06afff078) Å
SIFTS identifier: CAH2_HUMAN
Deposited: 20150625
Released / revised: 20160720 / 20251112

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	100.0%	100.0%	1–260

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A / A	Carbonic anhydrase 2polypeptide(L)	260 residues	not reported by the source	Genetically manipulated

Reading this structure

This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.

Snapshot provenance

Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:31Z	`raw/uniprot/entries/P00918.json`	`ed44906dd1b976f4c8b0399e9e3a7a4af09b673c035a201e218a4880821c1179`	Open exact source
2026-07-14T09:21:41Z	`raw/pdbe/mappings/5c8i.json`	`e97e60a9b2f2535266109630518d7ec7b8e0043495de4a2e76d198b92dbf152f`	Open exact source
2026-07-14T09:22:16Z	`raw/pdbe/summary/chunk-03.json`	`d318ed911ff2a8e3f25986a39c37baa2a3bb13c1d2a75d036924ca34ffa2b9cb`	Open exact source
2026-07-14T09:22:16Z	`raw/pdbe/experiment/chunk-03.json`	`8bbfae15de944b1cacdf21ee7a42caf9f09149a49b6fdf48f69df854b06973c9`	Open exact source
2026-07-14T09:22:17Z	`raw/pdbe/molecules/chunk-03.json`	`e94951408bdc68a6d0767211c754ae03dc74c4cf253ad3a7626c02d4aaba5eeb`	Open exact source