Source assertion

PDBe/SIFTS maps PDB 4G0C to UniProt P00918 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:4G0C:UNIPROT:P00918
Subject dossier: ca2
Source chain: uniprot + pdbe
Upstream record: 4G0C
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: In this release

Experimental structure

Neutron structure of acetazolamide-bound human carbonic anhydrase II reveal molecular details of drug binding.

PDB ID: 4G0C
Experimental method: Neutron Diffraction
Resolution: %!f(*float64=0x24b06affe990) Å
SIFTS identifier: CAH2_HUMAN
Deposited: 20120709
Released / revised: 20120919 / 20230913

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	100.0%	98.8%	4–260

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A / A	Carbonic anhydrase 2polypeptide(L)	257 residues	not reported by the source	Genetically manipulated

Reading this structure

This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.

Snapshot provenance

Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:31Z	`raw/uniprot/entries/P00918.json`	`ed44906dd1b976f4c8b0399e9e3a7a4af09b673c035a201e218a4880821c1179`	Open exact source
2026-07-14T09:21:45Z	`raw/pdbe/mappings/4g0c.json`	`2c3a4615b040cea6fc519147fea911af34374bbc893f505c1a264dad855d7119`	Open exact source
2026-07-14T09:22:14Z	`raw/pdbe/summary/chunk-02.json`	`79ac3fb4e9e30c8c858b4d8ed8bbe6f85e8e0d0e3630627a999691f40a3d330d`	Open exact source
2026-07-14T09:22:14Z	`raw/pdbe/experiment/chunk-02.json`	`e42f681713cd9cdce851cc48738b3c6e0f0c075d0006a640c484bcab84561898`	Open exact source
2026-07-14T09:22:15Z	`raw/pdbe/molecules/chunk-02.json`	`27833f4d4cb9a9bfcb110f6e551fe2a5ccef01ccea4dda947132af6c51bd66e6`	Open exact source