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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · Metabolism
Data

Compare two measurements

Choose two records and the server checks whether they can be compared: identity, endpoint, value, assay, conditions, molecular form, dependence, direction, evidence class and sources. When a rule fails, the result names it and what would be needed.

Choose two records

These cannot be compared

Endpoint mismatch: A Ki record and an IC50 record must remain distinct.

Left: fixture-endpoint-aP00918, Ki

= 12 nM, biochemical, pH 7.4

Right: fixture-endpoint-bP00918, IC50

= 12 nM, biochemical, pH 7.4

PARAMETER_TYPE_MISMATCH

parameter_type

Values differ: "Ki" versus "IC50".

Needed: Ki, Kd, IC50, EC50, Km, kcat and kcat/Km must remain separate endpoints.

How the rules work

  1. Compare only exact, versioned protein identities; names are not identifiers.
  2. Rank quantitative measurements only within one assay or an independently reviewed matched-protocol group.
  3. Keep Ki, Kd, IC50, EC50, Km, kcat and kcat/Km as separate endpoint types.
  4. Preserve source relation operators and raw values; a bound is not a point estimate.
  5. Keep experimental constructs, variants, tested molecular forms and conditions explicit.
  6. Display a refusal with actionable reasons whenever strict comparison requirements are not met.
Download the rules (JSON)