Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

AADAT transaminates 3HKYN to xanthurenate

3HKYN + glyoxylate → xanthurenate + Gly + H2O

Reactome: R-HSA-9972889
Compartment: cytosol
Rhea: RHEA:65901

Inputs

3HKYNCHEBI:58125, C10H12N2O4, cytosol
glyoxylateCHEBI:36655, C2HO3, cytosol

Outputs

xanthurenateCHEBI:71201, C10H6NO4, cytosol
GlyCHEBI:57305, C2H5NO2, cytosol
H2OCHEBI:15377, H2O, cytosol

Catalysed by

transaminase activity of AADAT dimer [cytosol]EC 2.6.1

AADAT transaminates 3HKYN to xanthurenate

Inputs

Outputs

Catalysed by

Literature