Unknown ALDH oxidizes methylimidazolealdehyde
methylimidazole-aldehyde + H2O + NAD(P)+ → 2 H+ + NAD(P)H + methylimidazole-acetate
- Reactome
- R-HSA-9970035
- Compartment
- cytosol
- Rhea
- RHEA:16186
Inputs
- methylimidazole-aldehydeCHEBI:28104, C6H8N2O, cytosol
- H2OCHEBI:15377, H2O, cytosol
- NAD(P)+R-ALL-428218, cytosol
Outputs
- 2 H+CHEBI:15378, H, cytosol
- NAD(P)HR-ALL-428206, cytosol
- methylimidazole-acetateCHEBI:132918, C6H7N2O2, cytosol
Catalysed by
- aldehyde dehydrogenase (NAD+) activity of Unknown aldehyde dehydrogenase [cytosol]EC 1.2.1.3
Literature
- Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes Sci Rep, 2017
- Alcohol-histamine interactions Alcohol Alcohol, 1999
- Aldehyde dehydrogenase (EC 1.2.1.3): comparison of subcellular localization of the third isozyme that dehydrogenates gamma-aminobutyraldehyde in rat, guinea pig and human liver Comp Biochem Physiol B, 1991