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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

GALM converts beta-D-GAL to alpha-D-GAL

beta-D-Gal → alpha-D-Gal

Reactome: R-HSA-9931853
Compartment: cytosol
Rhea: RHEA:28677

Inputs

beta-D-GalCHEBI:27667, C6H12O6, cytosol

Outputs

alpha-D-GalCHEBI:28061, C6H12O6, cytosol

Catalysed by

aldose 1-epimerase activity of GALM [cytosol]EC 5.1.3.3; UniProt Q96C23

Literature

Identification and characterisation of human aldose 1-epimerase FEBS Lett., 2003
Molecular structure of human galactose mutarotase J Biol Chem, 2004
Comparison of the enzymatic activities of human galactokinase GALK1 and a related human galactokinase protein GK2 Biochem Biophys Res Commun, 1995