Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Late core complex dimerizes

2 Late core complex monomer → Late core complex dimer

Reactome: R-HSA-9866162
Compartment: mitochondrial inner membrane
Rhea: None recorded

Inputs

2 Late core complex monomerR-HSA-9866126, mitochondrial inner membrane

Outputs

Late core complex dimerR-HSA-9866174, mitochondrial inner membrane

Literature

Biogenesis of the bc 1 Complex of the Mitochondrial Respiratory Chain J Mol Biol, 2018
Assembly of the Multi-Subunit Cytochrome bc 1 Complex in the Yeast Saccharomyces cerevisiae Int J Mol Sci, 2022
Architecture of Human Mitochondrial Respiratory Megacomplex I 2 III 2 IV 2 Cell, 2017