Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC

TIMM21:COX4:COX5A:COX6C + MT-CO1:Mg2+:PE:CL:MITRAC → MT-CO1:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C

Reactome: R-HSA-9865412
Compartment: mitochondrial inner membrane · mitochondrial intermembrane space
Rhea: None recorded

Inputs

TIMM21:COX4:COX5A:COX6CR-HSA-9865418, mitochondrial intermembrane space
MT-CO1:Mg2+:PE:CL:MITRACR-HSA-9865433, mitochondrial inner membrane

Outputs

MT-CO1:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6CR-HSA-9865410, mitochondrial inner membrane

TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC

Inputs

Outputs

Literature