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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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SLC51A:SLC51B transports bile salts from cytosol to extracellular region

bile salts and acids → bile salts and acids

Reactome
R-HSA-9733964
Compartment
cytosol · plasma membrane · extracellular region
Rhea
RHEA:71855, RHEA:72683, RHEA:75051, RHEA:71859, RHEA:71703, RHEA:71851

Inputs

Outputs

Catalysed by

  • bile acid transmembrane transporter activity of SLC51A:SLC51B [plasma membrane]

Literature

  1. OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia Hepatology, 2005
  2. Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter Biochem J, 2007