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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

Data

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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

DHFR dimer binds DHFR inhibitors

DHFR dimer + DHFR inhibitors → DHFR dimer:DHFR inhibitors

Reactome: R-HSA-9709109
Compartment: cytosol
Rhea: None recorded

Inputs

DHFR dimerR-HSA-1497822, cytosol
DHFR inhibitorsR-ALL-9709140, cytosol

Outputs

DHFR dimer:DHFR inhibitorsR-HSA-9709105, cytosol

Literature