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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate

L-Ala + glyoxylate → Gly + PYR

Reactome: R-HSA-904864
Compartment: mitochondrial matrix
Rhea: RHEA:24249

Inputs

L-AlaCHEBI:57972, C3H7NO2, mitochondrial matrix
glyoxylateCHEBI:36655, C2HO3, mitochondrial matrix

Outputs

GlyCHEBI:57305, C2H5NO2, mitochondrial matrix
PYRCHEBI:15361, C3H3O3, mitochondrial matrix

Catalysed by

L-alanine:glyoxylate transaminase activity of AGXT2 tetramer [mitochondrial matrix]EC 2.6.1.44

Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate

Inputs

Outputs

Catalysed by

Literature