Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

MECR dimer reduces tdec2-CoA to DEC-CoA

tdec2-CoA + NADPH + H+ → DEC-CoA + NADP+

Reactome: R-HSA-8952873
Compartment: mitochondrial matrix
Rhea: RHEA:44961

Inputs

tdec2-CoACHEBI:61406, C31H48N7O17P3S, mitochondrial matrix
NADPHCHEBI:57783, C21H26N7O17P3, mitochondrial matrix
H+CHEBI:15378, H, mitochondrial matrix

Outputs

DEC-CoACHEBI:61430, C31H50N7O17P3S, mitochondrial matrix
NADP+CHEBI:58349, C21H25N7O17P3, mitochondrial matrix

Catalysed by

trans-2-enoyl-CoA reductase (NADPH) activity of MECR dimer [mitochondrial matrix]EC 1.3.1.38

MECR dimer reduces tdec2-CoA to DEC-CoA

Inputs

Outputs

Catalysed by

Literature