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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ACP6 hydrolyses MYS-LPA

MYS-LPA + H2O → 1-MMG + Pi

Reactome: R-HSA-8878654
Compartment: mitochondrial matrix
Rhea: None recorded

Inputs

MYS-LPACHEBI:62833, C17H35O7P, mitochondrial matrix
H2OCHEBI:15377, H2O, mitochondrial matrix

Outputs

1-MMGCHEBI:75562, C17H34O4, mitochondrial matrix
PiCHEBI:43474, HO4P, mitochondrial matrix

Catalysed by

lysophosphatidic acid phosphatase activity of ACP6 [mitochondrial matrix]EC 3.1.3.106; UniProt Q9NPH0

Literature

Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6 Protein Cell, 2013
Isolation of a cDNA encoding human lysophosphatidic acid phosphatase that is involved in the regulation of mitochondrial lipid biosynthesis J. Biol. Chem., 1999