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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

STARD5 binds DCA, LCA

STARD5 + DCA, LCA → STARD5:DCA/LCA

Reactome: R-HSA-8873850
Compartment: cytosol
Rhea: None recorded

Inputs

STARD5R-HSA-196114, cytosol
DCA, LCAR-ALL-8873845, cytosol

Outputs

STARD5:DCA/LCAR-HSA-8873894, cytosol

Catalysed by

bile acid binding activity of STARD5 [cytosol]UniProt Q9NSY2

Literature

STARD5 specific ligand binding: comparison with STARD1 and STARD4 subfamilies Mol. Cell. Endocrinol., 2013
StAR-related lipid transfer domain protein 5 binds primary bile acids J. Lipid Res., 2012