STARD10 transports PC from ER membrane to lamellar body membrane
STARD10:LPCAT1:PC → STARD10:PC + LPCAT1
- Reactome
- R-HSA-8873834
- Compartment
- cytosol · endoplasmic reticulum membrane · lamellar body membrane
- Rhea
- None recorded
Inputs
- STARD10:LPCAT1:PCR-HSA-8873921, endoplasmic reticulum membrane
Outputs
- STARD10:PCR-HSA-8873863, lamellar body membrane
- LPCAT1R-HSA-1498772, endoplasmic reticulum membrane
Catalysed by
- lipid carrier activity of STARD10:LPCAT1:PC [endoplasmic reticulum membrane]
Literature
- StarD10, a START domain protein overexpressed in breast cancer, functions as a phospholipid transfer protein J. Biol. Chem., 2005
- Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity J. Biol. Chem., 2007
- Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) Specifically Interacts with Phospholipid Transfer Protein StarD10 to Facilitate Surfactant Phospholipid Trafficking in Alveolar Type II Cells J. Biol. Chem., 2015