Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

PTPN13:PLEKHA1,2 bind PI(3,4)P2

PTPN13:PLEKHA1,2 + PI(3,4)P2 → PTPN13:PLEKHA1,2:PIP2

Reactome: R-HSA-8870332
Compartment: plasma membrane
Rhea: None recorded

Inputs

PTPN13:PLEKHA1,2R-HSA-8870330, plasma membrane
PI(3,4)P2CHEBI:16152, C11H19O19P3R2, plasma membrane

Outputs

PTPN13:PLEKHA1,2:PIP2R-HSA-8870324, plasma membrane

Catalysed by

phosphatidylinositol bisphosphate binding activity of PTPN13:PLEKHA1,2 [plasma membrane]

PTPN13:PLEKHA1,2 bind PI(3,4)P2

Inputs

Outputs

Catalysed by

Literature