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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
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Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG

DAG + acyl-CoA → TAG + CoA-SH

Reactome: R-HSA-8848580
Compartment: endoplasmic reticulum membrane · cytosol
Rhea: None recorded

Inputs

DAGCHEBI:17815, C5H6O5R2, endoplasmic reticulum membrane
acyl-CoACHEBI:58342, C22H31N7O17P3SR, cytosol

Outputs

TAGCHEBI:17855, C6H5O6R3, endoplasmic reticulum membrane
CoA-SHCHEBI:57287, C21H32N7O16P3S, cytosol

Catalysed by

diacylglycerol O-acyltransferase activity of DGAT2L6 [endoplasmic reticulum membrane]EC 2.3.1.20; UniProt Q6ZPD8

Literature

Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily J. Biol. Chem., 2005