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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

DBI, ACBD7 bind MCFA-CoA and LCFA-CoA

DBI, (ACBD7) + MCFA-CoA, LCFA-CoA → DBI,ACBD7:MCFA-CoA,LCFA-CoA

Reactome: R-HSA-8848246
Compartment: endoplasmic reticulum lumen
Rhea: None recorded

Inputs

DBI, (ACBD7)R-HSA-8848239, endoplasmic reticulum lumen
MCFA-CoA, LCFA-CoAR-ALL-8848288, endoplasmic reticulum lumen

Outputs

DBI,ACBD7:MCFA-CoA,LCFA-CoAR-HSA-8848291, endoplasmic reticulum lumen

Literature

Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells Biochem. J., 2008
Acyl-CoA binding protein and epidermal barrier function Biochim. Biophys. Acta, 2014