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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Butanoyl-CoA+FAD => Crotonoyl-CoA+FADH2

FAD + BT-CoA + H+ → FADH2 + Crotonoyl-CoA

Reactome: R-HSA-77319
Compartment: mitochondrial matrix
Rhea: RHEA:30732

Inputs

FADCHEBI:57692, C27H30N9O15P2, mitochondrial matrix
BT-CoACHEBI:57371, C25H38N7O17P3S, mitochondrial matrix
H+CHEBI:15378, H, mitochondrial matrix

Outputs

FADH2CHEBI:58307, C27H33N9O15P2, mitochondrial matrix
Crotonoyl-CoACHEBI:57332, C25H36N7O17P3S, mitochondrial matrix

Catalysed by

acyl-CoA dehydrogenase activity of ACADS tetramer [mitochondrial matrix]EC 1.3.99.3

Butanoyl-CoA+FAD => Crotonoyl-CoA+FADH2

Inputs

Outputs

Catalysed by

Literature