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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA

trans-Hexadec-2-enoyl-CoA + H2O → (S)-3-Hydroxyhexadecanoyl-CoA

Reactome: R-HSA-77301
Compartment: mitochondrial matrix
Rhea: RHEA:31165

Inputs

trans-Hexadec-2-enoyl-CoACHEBI:61526, C37H60N7O17P3S, mitochondrial matrix
H2OCHEBI:15377, H2O, mitochondrial matrix

Outputs

(S)-3-Hydroxyhexadecanoyl-CoACHEBI:62613, C37H62N7O18P3S, mitochondrial matrix

Catalysed by

enoyl-CoA hydratase activity of Trifunctional Protein [mitochondrial matrix]EC 4.2.1.17

Literature

Human liver long-chain 3-hydroxyacyl-coenzyme A dehydrogenase is a multifunctional membrane-bound beta-oxidation enzyme of mitochondria. Biochem Biophys Res Commun, 1992