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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

2-trans-Dodecenoyl-CoA+H2O =>( S)-3-Hydroxydodecanoyl-CoA

H2O + 2-trans-Dodecenoyl-CoA → (S)-3-Hydroxydodecanoyl-CoA

Reactome: R-HSA-77256
Compartment: mitochondrial matrix
Rhea: RHEA:31077

Inputs

H2OCHEBI:15377, H2O, mitochondrial matrix
2-trans-Dodecenoyl-CoACHEBI:57330, C33H52N7O17P3S, mitochondrial matrix

Outputs

(S)-3-Hydroxydodecanoyl-CoACHEBI:62558, C33H54N7O18P3S, mitochondrial matrix

Catalysed by

enoyl-CoA hydratase activity of ECHS1 hexamer [mitochondrial matrix]EC 4.2.1.17

Literature

Enzymes of fatty acid metabolism. II. Properties of crystalline crotonase. J Biol Chem, 1956