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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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Ethylene is oxidized to Ethylene oxide by CYP1A1

C2H4 + O2 + NADPH + H+ → EtO + H2O + NADP+

Reactome
R-HSA-76472
Compartment
endoplasmic reticulum membrane · endoplasmic reticulum lumen · smooth endoplasmic reticulum
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • monooxygenase activity of CYP1A1 [endoplasmic reticulum membrane]UniProt P04798

Literature

  1. Cytochrome P450 oxidations in the generation of reactive electrophiles: epoxidation and related reactions Arch Biochem Biophys, 2003
  2. Destruction of cytochrome P-450 by ethylene. Structure of the resulting prosthetic heme adduct. J Biol Chem, 1981