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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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APRT catalyzes the conversion of adenine to AMP

Ade + PRPP → AMP + PPi

Reactome
R-HSA-74213
Compartment
cytosol
Rhea
RHEA:16611

Inputs

Outputs

Catalysed by

  • adenine phosphoribosyltransferase activity of APRT dimer [cytosol]EC 2.4.2.7

Literature

  1. Human adenine phosphoribosyltransferase. Affinity purification, subunit structure, amino acid composition, and peptide mapping. J Biol Chem, 1979
  2. Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism J Biomol Struct Dyn, 2008