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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA

ACA + SUCC-CoA → ACA-CoA + SUCCA

Reactome: R-HSA-74177
Compartment: mitochondrial matrix
Rhea: RHEA:25481

Inputs

ACACHEBI:15344, C4H6O3, mitochondrial matrix
SUCC-CoACHEBI:57292, C25H35N7O19P3S, mitochondrial matrix

Outputs

ACA-CoACHEBI:57286, C25H36N7O18P3S, mitochondrial matrix
SUCCACHEBI:30031, C4H4O4, mitochondrial matrix

Catalysed by

succinyl-CoA:3-oxo-acid CoA-transferase activity of OXCT dimers [mitochondrial matrix]EC 2.8.3.5

OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA

Inputs

Outputs

Catalysed by

Literature