Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

AICAR + 10-Formyl-THF => FAICAR + THF

AICAR + 10-formyl-THF → FAICAR + THF

Reactome: R-HSA-73798
Compartment: cytosol
Rhea: RHEA:22193

Inputs

AICARCHEBI:58475, C9H13N4O8P, cytosol
10-formyl-THFCHEBI:195366, C20H21N7O7, cytosol

Outputs

FAICARCHEBI:58467, C10H13N4O9P, cytosol
THFCHEBI:57453, C19H21N7O6, cytosol

Catalysed by

phosphoribosylaminoimidazolecarboxamide formyltransferase activity of ATIC dimer [cytosol]EC 2.1.2.3

AICAR + 10-Formyl-THF => FAICAR + THF

Inputs

Outputs

Catalysed by

Literature