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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

FAICAR => IMP + H2O

FAICAR → IMP + H2O

Reactome: R-HSA-73797
Compartment: cytosol
Rhea: RHEA:18447

Inputs

FAICARCHEBI:58467, C10H13N4O9P, cytosol

Outputs

IMPCHEBI:58053, C10H11N4O8P, cytosol
H2OCHEBI:15377, H2O, cytosol

Catalysed by

IMP cyclohydrolase activity of ATIC dimer [cytosol]EC 3.5.4.10

FAICAR => IMP + H2O

Inputs

Outputs

Catalysed by

Literature