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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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hydrolysis of 2'-deoxyuridine 5'-triphosphate to form 2'-deoxyuridine 5'-phosphate

dUTP + H2O → dUMP + PPi + H+

Reactome
R-HSA-73666
Compartment
nucleoplasm
Rhea
RHEA:10249

Inputs

Outputs

Catalysed by

  • dUTP diphosphatase activity of DUT trimer [nucleoplasm]EC 3.6.1.23

Literature

  1. Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits Structure, 1996
  2. Characterization of distinct nuclear and mitochondrial forms of human deoxyuridine triphosphate nucleotidohydrolase J Biol Chem, 1996