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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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Regeneration of active (reduced) Thioredoxin

2xHC-TXN + NADPH + H+ → TXN + NADP+

Reactome
R-HSA-73646
Compartment
cytosol
Rhea
RHEA:20347

Inputs

Outputs

Catalysed by

  • thioredoxin-disulfide reductase (NADPH) activity of TNXRD1:FAD dimer [cytosol]EC 1.8.1.9

Literature

  1. Truncated mutants of human thioredoxin reductase 1 do not exhibit glutathione reductase activity FEBS Lett, 2006