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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2

ACS + H+ → 2AMA + CO2

Reactome
R-HSA-71223
Compartment
cytosol
Rhea
RHEA:16558

Inputs

Outputs

Catalysed by

  • carboxy-lyase activity of ACMSD dimer [cytosol]EC 4.1.1

Literature

  1. Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis". J Biol Chem, 2002