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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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PXLP-K314-GPT transaminates L-Ala to form PYR

L-Ala + 2OG → PYR + L-Glu

Reactome
R-HSA-70523
Compartment
cytosol
Rhea
RHEA:19454

Inputs

Outputs

Catalysed by

  • L-alanine:2-oxoglutarate transaminase activity of PXLP-K314-GPT dimer [cytosol]EC 2.6.1.2

Literature

  1. Complete amino acid sequence of human liver cytosolic alanine aminotransferase (GPT) determined by a combination of conventional and mass spectral methods Biochemistry, 1991
  2. Human glutamate pyruvate transaminase (GPT): localization to 8q24.3, cDNA and genomic sequences, and polymorphic sites. Genomics, 1997
  3. cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase Genomics, 2002