GAPDH tetramers reduce 1,3BPG to GA3P
1,3BPG + NADH + H+ → GA3P + Pi + NAD+
- Reactome
- R-HSA-70482
- Compartment
- cytosol
- Rhea
- RHEA:10302
Inputs
- 1,3BPGCHEBI:57604, C3H4O10P2, cytosol
- NADHCHEBI:57945, C21H27N7O14P2, cytosol
- H+CHEBI:15378, H, cytosol
Outputs
- GA3PCHEBI:59776, C3H5O6P, cytosol
- PiCHEBI:43474, HO4P, cytosol
- NAD+CHEBI:57540, C21H26N7O14P2, cytosol
Catalysed by
- glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity of GAPDH tetramers [cytosol]EC 1.2.1.12
Literature
- Glyceraldehyde-3-phosphate dehydrogenase from human tissues. Methods Enzymol, 1983
- Isozymes of glyceraldehyde-3-phosphate dehydrogenase in man and other mammals. Ann Hum Genet, 1976
- Human glyceraldehyde 3-phosphate dehydrogenase-2 gene is expressed specifically in spermatogenic cells. J Androl, 2000
- Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene J Biol Chem, 1988