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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

TPI1 dimer isomerizes DHAP to GA3P

DHAP → GA3P

Reactome: R-HSA-70454
Compartment: cytosol
Rhea: RHEA:18587

Inputs

DHAPCHEBI:57642, C3H5O6P, cytosol

Outputs

GA3PCHEBI:59776, C3H5O6P, cytosol

Catalysed by

triose-phosphate isomerase activity of TPI1 dimer [cytosol]EC 5.3.1.1

Literature

Primary structure of human triosephosphate isomerase J Biol Chem, 1984
Structure of a high-resolution crystal form of human triosephosphate isomerase: improvement of crystals using the gel-tube method Acta Crystallogr Sect F Struct Biol Cryst Commun, 2005