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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P

ATP + Glc → ADP + G6P + H+

Reactome: R-HSA-70420
Compartment: cytosol
Rhea: RHEA:17826

Inputs

ATPCHEBI:30616, C10H12N5O13P3, cytosol
GlcCHEBI:4167, C6H12O6, cytosol

Outputs

ADPCHEBI:456216, C10H12N5O10P2, cytosol
G6PCHEBI:58225, C6H11O9P, cytosol
H+CHEBI:15378, H, cytosol

Catalysed by

glucokinase activity of glucokinase and hexokinases [cytosol]EC 2.7.1.2

Literature