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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Arrows follow Reactome's curated reaction direction.

ENPP6 hydrolyzes lysophosphatidylcholine

lysophosphatidylcholine + H2O → ChoP + MAG

Reactome: R-HSA-6814797
Compartment: plasma membrane · extracellular region
Rhea: None recorded

Inputs

lysophosphatidylcholineCHEBI:60479, C9H19NO7PR, plasma membrane
H2OCHEBI:15377, H2O, extracellular region

Outputs

ChoPCHEBI:18132, C5H15NO4P, extracellular region
MAGCHEBI:17408, C4H7O4R, extracellular region

Catalysed by

glycerophosphocholine cholinephosphodiesterase activity of ENPP6 [plasma membrane]EC 3.1.4.38; UniProt Q6UWR7

Literature

Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family J. Biol. Chem., 2005