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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

I(1,3)P2 is dephosphorylated into I1P by MTMR7

I(1,3)P2 + H2O → I1P + Pi

Reactome: R-HSA-6809561
Compartment: cytosol
Rhea: RHEA:57841

Inputs

I(1,3)P2CHEBI:83242, C6H10O12P2, cytosol
H2OCHEBI:15377, H2O, cytosol

Outputs

I1PCHEBI:58433, C6H11O9P, cytosol
PiCHEBI:43474, HO4P, cytosol

Catalysed by

inositol bisphosphate phosphatase activity of MTMR7 [cytosol]EC 3.1.3; UniProt Q9Y216

Literature

Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9 Proc Natl Acad Sci U S A, 2003