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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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BPHL hydrolyses VACV to ACV

VACV + H2O → ACV + L-Val

Reactome
R-HSA-6784959
Compartment
cytosol · mitochondrial outer membrane
Rhea
RHEA:83872

Inputs

Outputs

Catalysed by

Literature

  1. Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase J. Biol. Chem., 2003
  2. Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase J. Biol. Chem., 2008