Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG

MAG + Acyl-CoA → DAG + CoA-SH

Reactome: R-HSA-5696448
Compartment: endoplasmic reticulum membrane · cytosol
Rhea: None recorded

Inputs

MAGCHEBI:17408, C4H7O4R, endoplasmic reticulum membrane
Acyl-CoACHEBI:58342, C22H31N7O17P3SR, endoplasmic reticulum membrane

Outputs

DAGCHEBI:17815, C5H6O5R2, endoplasmic reticulum membrane
CoA-SHCHEBI:57287, C21H32N7O16P3S, cytosol

Catalysed by

2-acylglycerol O-acyltransferase activity of AWAT2 [endoplasmic reticulum membrane]EC 2.3.1.22; UniProt Q6E213

AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG

Inputs

Outputs

Catalysed by

Literature