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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH

aspartame + H2O → L-Asp + L-Phe + MeOH

Reactome: R-HSA-5696365
Compartment: cytosol
Rhea: None recorded

Inputs

aspartameCHEBI:195544, C14H18N2O5, cytosol
H2OCHEBI:15377, H2O, cytosol

Outputs

L-AspCHEBI:29991, C4H6NO4, cytosol
L-PheCHEBI:58095, C9H11NO2, cytosol
MeOHCHEBI:17790, CH4O, cytosol

Catalysed by

omega peptidase activity of ASRGL1 heterodimer [cytosol]EC 3.4.19.1

Literature