Skip to content

DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

Data

Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

AOC3 deaminates BZAM

BZAM + H2O + O2 → NH3 + H2O2 + H+ + BZAL

Reactome: R-HSA-5696183
Compartment: extracellular region · plasma membrane
Rhea: RHEA:59425

Inputs

BZAMCHEBI:225238, C7H10N, extracellular region
H2OCHEBI:15377, H2O, extracellular region
O2CHEBI:15379, O2, extracellular region

Outputs

NH3CHEBI:16134, H3N, extracellular region
H2O2CHEBI:16240, H2O2, extracellular region
H+CHEBI:15378, H, extracellular region
BZALCHEBI:17169, C7H6O, extracellular region

Catalysed by

primary methylamine oxidase activity of AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane]EC 1.4.3.21

Literature

Cloning of vascular adhesion protein 1 reveals a novel multifunctional adhesion molecule J. Exp. Med., 1998
Adipogenesis-related increase of semicarbazide-sensitive amine oxidase and monoamine oxidase in human adipocytes Biochimie, 2007
The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase Cell. Mol. Life Sci., 2009