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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

AGMO cleaves alkylglycerol into fatty aldehyde and glycerol

alkylglycerol + O2 + BH4 → fatty aldehyde + Glycerol + H2O + q-BH2

Reactome: R-HSA-5696119
Compartment: endoplasmic reticulum membrane · endoplasmic reticulum lumen
Rhea: None recorded

Inputs

alkylglycerolCHEBI:52575, cytosol
O2CHEBI:15379, O2, cytosol
BH4CHEBI:59560, C9H15N5O3, cytosol

Outputs

fatty aldehydeCHEBI:35746, CHOR, cytosol
GlycerolCHEBI:17754, C3H8O3, cytosol
H2OCHEBI:15377, H2O, cytosol
q-BH2CHEBI:43029, C9H13N5O3, cytosol

Catalysed by

glyceryl-ether monooxygenase activity of AGMO [endoplasmic reticulum membrane]EC 1.14.16.5; UniProt Q6ZNB7

Literature

Identification of the gene encoding alkylglycerol monooxygenase defines a third class of tetrahydrobiopterin-dependent enzymes Proc. Natl. Acad. Sci. U.S.A., 2010