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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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ADPGK:Mg2+ phosphorylates Glc to G6P

Glc + ADP → G6P + AMP + H+

Reactome
R-HSA-5696021
Compartment
endoplasmic reticulum membrane · cytosol
Rhea
RHEA:11461

Inputs

Outputs

Catalysed by

  • ADP-specific glucokinase activity of ADPGK:Mg2+ [endoplasmic reticulum membrane]EC 2.7.1.147

Literature

  1. T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation Cell Rep, 2012
  2. Expression and role in glycolysis of human ADP-dependent glucokinase Mol. Cell. Biochem., 2012