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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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ALD3A1 oxidises 4HPCP to CXPA

4HPCP + H2O + NADP+ → CXPA + H+ + NADPH

Reactome
R-HSA-5692283
Compartment
cytosol
Rhea
None recorded

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Catalysed by

Literature

  1. RNAi-mediated knockdown of aldehyde dehydrogenase class-1A1 and class-3A1 is specific and reveals that each contributes equally to the resistance against 4-hydroperoxycyclophosphamide Cancer Chemother. Pharmacol., 2007
  2. Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity Chembiochem, 2014